Erectile dysfunction is defined as the incapability of achieving or maintaining sufficient penile erection to experience satisfactory intercourse. The prevalence of erectile dysfunction increases with age, and it mainly affects men aged >40 years. Erectile dysfunction is estimated to affect 322 million men worldwide by 2025, and erectile dysfunction is considered a major public health concern for the increasing ageing male population. Erectile dysfunction is mainly caused by organic and psychogenic factors. Rigid erections in the morning, night, or at any sexual thought indicate psychogenic erectile dysfunction. Furthermore, psychogenic erectile dysfunction frequently presents with a sudden onset, intermittent course, or short duration. By contrast, organic erectile dysfunction frequently presents with a gradual onset, progressive course, or long duration. The development of erectile dysfunction has been associated with diabetes, hypertension, hyperlipidemia, depression, and metabolic syndrome. Moreover, erectile dysfunction is considered a marker of cardiovascular disorders. In fact, organic erectile dysfunction could anticipate a heart attack by a few months.