Heart attack risk after stone procedure linked to metabolic syndrome


Metabolic syndrome is a cluster of conditions - increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels - that occur together, increasing your risk of heart disease, stroke and diabetes.Patients with metabolic syndrome (MetS) are at higher risk of myocardial infarction after undergoing percutaneous nephrolithotomy (PCNL).

The incidence of postoperative myocardial infarction (MI) increased from 0.6% of patients with no MetS conditions, 1.0% of those with 1-2 MetS conditions, and 1.8% of those with 3-4 MetS conditions. 

On multivariate analysis, patients with 3-4 MetS conditions had significant 2.2-fold increased odds of postoperative MI compared with those who had no MetS conditions. The odds of MI were not significantly increased among patients with 1-2 MetS conditions.


Johans CE, Bajic P, Kirshenbaum E, et al. Metabolic syndrome increases risk of postoperative myocardial infarction following percutaneous nephrolithotomy. J Endourol. 2018; published online ahead of print.