High-grade Prostate Cancer risk is related to higher levels of cholesterol


High serum levels of total and HDL cholesterol are associated with an elevated risk of high-grade prostate cancer.

The new study provides yet one more reason for people to watch their cholesterol and dovetails with some data that statins may have benefits for prostate cancer.

Given the anti-inflammatory, anti-proliferative, and antioxidant properties of HDL, it is unclear why high HDL would be associated with an increased risk of PCa.

However, these data support a role for cholesterol, a modifiable risk factor, in aggressive prostate cancer.

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