Nocturia may lead abnormal nocturnal blood pressure


Poor sleep quality, particularly from frequent urination at night, is strongly associated with nighttime blood pressure (BP) abnormalities

The researchers analyzed data from 5959 men and women. Participants measured sleep onset and awake time, sleep duration, sleep fragmentation, sleep disordered breathing, and nocturnal voids at home using various tools, including actigraphy, 3% oxygen desaturation index monitors, and sleep diaries.

According to results in the Journal of Hypertension, systolic BP decreased 8.5% on average. Having a higher number of nighttime voids, however, significantly correlated with smaller dips in nocturnal BP. Other associations with BP became nonsignificant after adjustment, including the sleep fragmentation index and 3% oxygen desaturation index.

Subjective sleep estimates and frequent nocturnal urination may represent a potential risk for circadian BP abnormalities.

Clinicians should ask more carefully about the presence and/or the number of nocturnal voids in all patients and not only in elderly, especially male, individuals.


Matsumoto T, Tabarab Y, Murase K, et al. Nocturia and increase in nocturnal blood pressure: the Nagahama study. J Hypertension 36:2185-2192. DOI:10.1111/bju.14535