Pregnant Stone Formers Have Higher Risk of Gestational Diabetes


Women with a history of kidney stone formation are at elevated risk of gestational diabetes and preeclampsia.

In a retrospective cohort study of women who delivered infants at Massachusetts General Hospital in Boston from 2006 to 2015, investigators found that gestational diabetes and preeclampsia occurred significantly more frequently among stone formers than women without a history of stone formation (18% vs 6%, respectively, and 16% vs 8%, respectively)

Additionally, infants of stone formers were born significantly earlier (38.7 vs 39.2 weeks). The rates of small for gestational age offspring and neonatal intensive care admission were not significantly between stone formers and non-stone formers (8% and 7%, respectively, and 10% and 6%, respectively).

In conclusion, the history of kidney stones identifies women at higher risk for metabolic and hypertensive complications in pregnancy,

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