The Magnetic Resonance Imaging-Buided Biopsy is more accurate in defining the real Gleason Score at the biopsy

19.11.2018

Magnetic Resonance Imaging Guided Biopsy may enhance the diagnostic accuracy of prostate cancer detection in final histopathology with lower rate of upgraded Gleason Score than Transrectal Ultrasound Guided Biopsy.

Clinicians depend heavily on the prostate biopsy Gleason score (GS) to predict tumor aggressiveness and counsel patients for further treatment. Accurate assessment of tumor aggressiveness is essential in diagnosing PCa. The GS between prostate biopsy and radical prostatectomy (RP) specimens is occasionally discordant. As a result, PCa risk may be underestimated and patients might not obtain adequate medical care. Reportedly, GS is underestimated in up to 43% of patients, compared with their radical prostatectomy (RP) specimens.

The Authors found out that MRI-GB may enhance the diagnostic accuracy of prostate cancer detection in final histopathology with lower rate of upgraded GS than TRUS-GB, which may contribute to better therapeutic decisions.

Reference

Ning Xu, Yu-Peng Wu, Xiao-Dong Li, Min-Yi Lin, Qing-Shui Zheng, Shao-Hao Chen, Jun-Feng Li, Yong Wei,and Xue-Yi Xue. Risk of upgrading from prostate biopsy to radical prostatectomy pathology: Is magnetic resonance imaging-guided biopsy more accurate?J Cancer. 2018; 9(19): 3634-3639.

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